Instrument for characterization of biomolecular phase transitions

Name of applicant

Magnus Kjærgaard


Aarhus University


DKK 1,234,240



Type of grant

Research Infrastructure


Like houses, living cells are divided into different rooms with different functions. These "rooms" are known as organelles. Recently, a fundamentally new type of organelle has been discovered that is not bounded by membranes, which is akin to a room without walls. Instead, these organelles form by spontaneous assembly of biological macromolecules: proteins, RNA and DNA. To study such organelles, we need new equipment that can describe the self-assembly of into liquid-like droplets. This grant will enable us to acquire an instrument that can track the self-assembly of macromolecules and the tiny protein droplets formed. The instrument will be used in a range of projects describing how such membrane less organelles are perturbed in disease as well as engineering of new biomaterials.

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